• About ArQule
• Product R & D
  • Pipeline
  • Activated Checkpoint Therapy® Platform
  • C-Met/Cancer Survival Protein Platform
  • Glossary
• Clinical Trials
• Investors and Media
• Careers

Glossary

Angiogenesis	The process by which new blood vessels are formed.
Apoptosis	Cell suicide that is genetically determined or environmentally induced. The destruction of cells from within follows a programmed biochemical event.
Cell Cycle	The sequence of events between cell divisions. The cycle is conventionally divided into G0, G1, S, G2 and M phases.
Checkpoint	Internal surveillance mechanism that stops the cell cycle when there is a problem (e.g. DNA damage).
Ligand	A molecule that binds to a receptor or protein.
Metastasis	The spread of cancer from one part of the body to another.
Mitosis	Phase of the cell cycle in which the chromosomes separate.
Oncogenesis	The formation and development of tumors.
Receptor tyrosine kinase	A class of cell membrane receptors which may play significant roles in cell division.
S-phase	Phase of the cell cycle in which the DNA doubles.