Pipeline

Portfolio Updated February 2012

¹ Pre-GLP toxicology testing
² Post-initiation of GLP toxicology testing
³ Designation follows initation of first patient enrollment and dosing in lead indication
⁴ U.S., Europe, South America and the rest of the world, excluding Japan and select Asian countries
⁵ Japan and select Asian countries
⁶ See corporate slide presentation here for the status of all ongoing trials with ARQ 197.