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Home : Product R & D : Scientific Publications

Scientific Publications

2006

Wilson C, et al.
Identification of a Small Molecule That Induces Mitotic Arrest Using a Simplified High-Content Screening Assay and Data Analysis Method

Journal of Biomolecular Screening 11 (1); 2006

2005

Zhang, B., et al.

Development of a High-Throughput Robotic Fluorescence-Based Assay for HsEg5 Inhibitor Screening

Analytical Biochemistry 2005; 345(2):  326-35

Wang A, Li CJ, Reddy PV, Pardee AB.
Cancer Chemotherapy by Deoxynucleotide Depletion and E2F-1 Elevation
Cancer Research, 2005; 65(17), September 1, 2005

Chen C, et al.
Dual Induction of Apoptosis and Senescence in Cancer Cells by Chk2 Activation: Checkpoint Activation as a Strategy Against Cancer
Cancer Research, 2005; 65: (14), July 15, 2005

Gorgoulis, et al.
Activation of the DNA Damage Checkpoint and Genomic Instability in Human Precancerous Lesions
Nature, Vol 434, 14 April 2005

Bartkova, et al.
DNA Damage Response as a Candidate Anti-Cancer Barrier in Early Human Tumorigenesis
Nature, Vol 434, 14 April 2005

Venkitaraman, A
Aborting the Birth of Cancer
News and Views, Nature, Vol 434, 14 April 2005

2004

Ali S, et al.
Identification and Characterization of Inhibitors of Bacterial Enoyl-Acyl Carrier Protein Reductase
Antimicrobial Agents and Chemotherapy; 2004 May; 48(5):1541-1547

Ashwell MA, et al.
The Design, Preparation and SAR of Novel Small Molecule Sodium (NA(+) Channel Blockers
Bioorganic Medicinal Chemistry Letters; 2004 May 3; 14(9):2025-30

Tandon M, et al.
The Design and Preparation of Metabolically Protected New Arylpiperazine 5-HT1A Ligands
Bioorganic Medicinal Chemistry Letters; 2004 April 5; 14(7):1709-12

Tandon M, et al.
Potent and Selective Inhibitors of Bacterial Methionyl tRNA Synthetase Derived from an Oxazolone-dipeptide Scaffold
Bioorganic Medicinal Chemistry Letters; 2004 April 19; 14(8):1909-11

2003

Li, Y, et al.
Selective Killing of Cancer Cells by Beta - Lapachone: Direct Checkpoint Activation as a Strategy Against Cancer
Proc Natl Acad Sci U S A; March 4, 2003; 100(5):2674-8

1999

Li CJ, et al.
Potent Inhibition of Tumor Survival In Vivo by Beta-Lapachone Plus Taxol: Combining Drugs Imposes Different Artificial Checkpoints
Proc Natl Acad Sci U S A; November 9, 1999; 96(23):13369-74

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